Alpha-Arbutin Powder CAS 84380-01-8
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Purity: ≥ 99% (HPLC)
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CAS No.: 84380-01-8
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Appearance: Fine white crystalline powder
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Solubility: Highly water-soluble
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Key Benefit: Superior skin brightening by inhibiting tyrosinase activity without toxicity.
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Compliance: REACH registered, SDS/TDS available.
अल्फा-आर्बुटिन बनाम ग्लूटाथियोन बनाम कोजिक एसिड: बी2बी खरीदारों के लिए सोर्सिंग गाइड
“Wholesale Pricing Available”
“Global Shipping – Technical Support Included”
Description
“Discover more in our Whitening Ingredients catalog.”
The Gold Standard in Skin Brightening: Alpha-Arbutin
In the evolving landscape of cosmeceuticals, Alpha-Arbutin (CAS 84380-01-8) has emerged as the most reliable and efficient skin-lightening agent. Unlike its isomer Beta-Arbutin, Alpha-Arbutin is a pure, water-soluble, biosynthetic active ingredient that offers a higher degree of stability and efficacy. At Onerchem, we provide premium-grade Alpha-Arbutin with a purity exceeding 99%, ensuring your formulations meet the highest international standards for safety and performance.
I. Comprehensive Technical Profile
| Parameter | Technical Standard (Onerchem Grade) |
|---|---|
| Chemical Name | 4-Hydroxyphenyl-α-D-glucopyranoside |
| Molecular Formula / Weight | C12H16O7 / 272.25 g/mol |
| Source | Biosynthesis (Enzymatic synthesis) |
| Assay (HPLC) | ≥ 99.5% |
| Clarity of Solution | Colorless, Transparent, No Suspended Matter |
| Heavy Metals (Pb, As, Hg, Cd) | Total ≤ 10ppm; Individual < 1ppm |
| Hydroquinone Content | Strictly < 10ppm (NMT 0.001%) |
| Microbial Limit | Total Plate Count < 100cfu/g; No Pathogens |
II. Mechanism of Action: The Science of Inhibition
The primary function of Alpha-Arbutin is the inhibition of Tyrosinase—the key enzyme responsible for melanin production in the skin. While other whitening agents can be cytotoxic or irritating, Alpha-Arbutin works through a competitive inhibition mechanism:
1. Competitive Inhibition
Alpha-Arbutin mimics the substrate of tyrosinase, blocking the oxidation of L-DOPA. This prevents the formation of dopaquinone, the precursor to both eumelanin and pheomelanin.
2. Melanosome Maturation
It interferes with the maturation of melanosomes, effectively reducing the pigment density in the basal layer of the epidermis without damaging the melanocytes themselves.
III. Alpha vs. Beta Arbutin: Why Quality Matters
Research indicates that Alpha-Arbutin is more than 10 times more effective than Beta-Arbutin. The α-glucosidic linkage offers higher stability toward heat and light. In clinical trials, Alpha-Arbutin showed a significantly higher response rate in reducing the appearance of age spots and hyperpigmentation within 4 weeks of consistent use.
IV. Advanced Formulation Guide for R&D Engineers
Successful incorporation of Alpha-Arbutin requires precise control of the formulation environment. Our technical team suggests the following:
- Solubility: Highly soluble in water. It should be dissolved in the aqueous phase.
- pH Sensitivity: Most stable between pH 3.5 - 6.5. Avoid pH > 7.0 to prevent hydrolysis.
- Temperature Control: Do not expose to temperatures above 40°C for extended periods. Add during the cool-down phase of the emulsion process.
- Synergistic Combinations:
With Vitamin C (MAP/SAP) With Niacinamide With AHAs
V. Global Regulatory Compliance & Safety
Onerchem’s Alpha-Arbutin is manufactured in compliance with global cosmetic safety regulations:
EU SCCS Compliance
Our material meets the safety limits suggested by the Scientific Committee on Consumer Safety (SCCS) for face creams (2%) and body lotions (0.5%).
Eco-Friendly
Biosynthetic process minimizes chemical waste, aligning with "Green Chemistry" and "Clean Beauty" trends.
VI. Frequently Asked Questions (FAQ)
Q: Can Alpha-Arbutin be used during the day?
A: Yes. Unlike Retinol, Alpha-Arbutin does not increase skin sensitivity to the sun. However, we always recommend pairing it with a broad-spectrum SPF for maximum results.
Q: Is it safe for sensitive skin?
A: Absolutely. It is considered a gentle alternative to hydroquinone, making it suitable for all skin types, including sensitive and acne-prone skin.
Ready to Enhance Your Skin Brightening Line?
Contact Onerchem today for a Free Sample, COA, and Batch Specific TDS.
REQUEST QUOTE NOW🔬 In-Depth Science: Why Alpha-Arbutin Over Beta-Arbutin?
Many buyers ask why Alpha-Arbutin is significantly more expensive than the Beta version. The answer lies in the Alpha-Glucosidic linkage. This specific molecular structure offers higher stability and faster tyrosinase inhibition. Research shows that Alpha-Arbutin is 10 times more effective even at lower concentrations.
| Feature | Alpha-Arbutin (Onerchem) | Beta-Arbutin |
|---|---|---|
| Stability | ⭐⭐⭐⭐⭐ (Excellent) | ⭐⭐ (Poor to Light) |
| Whitening Effect | 90% Inhibition Rate | 30-40% Inhibition Rate |
| Production Method | Biosynthesis (Enzymatic) | Chemical Synthesis |
🧪 Advanced Formulation Strategy
To ensure Onerchem Alpha-Arbutin maintains its efficacy throughout the shelf life of your cosmetic product, our lab team recommends the following technical steps:
Phase Addition: Dissolve in the water phase at the end of the process.
Temperature: Keep the temperature below 40°C during addition to avoid degradation.
pH Environment: Maintain the final product pH between 4.5 and 6.0 for peak stability.
🌍 Sustainable Sourcing & Logistics
As a leading supplier in the Onerchem network, our Alpha-Arbutin is produced via an eco-friendly enzymatic process, aligning with Clean Beauty and Green Chemistry standards. We provide standardized 1kg/25kg packaging with dual-layer moisture-proof protection, ensuring international shipping safety to Europe, North America, and Asia.
Formulation Support Available
This ingredient is a core component of our Whitening Application Solutions.
In-depth Technical Comparison
Alpha Arbutin vs. Niacinamide: Which one fits your formula best?
Additional information
| INCI Name |
Alpha-Arbutin |
|---|---|
| Chemical Name |
4-Hydroxyphenyl-α-D-glucopyranoside |
| Melting Point |
203 – 207℃ |
| pH (1% solution) |
5.0 – 7.0 |
| Heavy Metals |
≤ 10 ppm |
| Recommended Dosage |
0.2% – 2.0% |
| Solution | |
| Technical Group | |
| Technical Keywords |
Tyrosinase Inhibition ,Hydroquinone Derivative |
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Shipping and Delivery
Onerchem B2B
✈ Ships from China
Shipping &
Delivery
All orders ship from our facility in mainland China. Samples are dispatched within 7 working days. Bulk orders follow a confirmed production schedule — with full documentation in every parcel.
≤7
Days · Sample dispatch
15–40
Days · Bulk lead time
Global
EU · GCC · ASEAN · NA
COA
Included every shipment
Dispatch Timeline
When does my order ship?
Dispatch timelines differ between sample and bulk orders. A confirmed dispatch date is always provided at order confirmation.
Sample Orders
≤7 working days
From order confirmation to dispatch
Samples are QC-checked, weighed, and packed individually. Your COA and MSDS are printed and included in the parcel before sealing. Most sample orders ship ahead of the 7-day window.
Tracking number provided on dispatch · Express courier available on request
Bulk Orders
15–40 working days
Varies by quantity and specification
Lead time is determined by order volume, packaging format, and whether custom labelling or documentation is required. A production and dispatch schedule is confirmed in writing at the time of order.
Schedule confirmed at order · Progress updates available on request
Process
From order to delivery
Four steps from confirmed order to goods in hand.
01
Order Confirmed
Written confirmation sent within 1 business day. Dispatch schedule and freight quote included for bulk orders.
02
QC & Packing
Batch is QC-checked against HPLC data. COA and MSDS are generated and packed with the shipment.
03
Dispatch
Shipment handed to carrier. Tracking number and commercial invoice sent to buyer by email on the same day.
04
Delivery
Goods arrive at destination. 7 working-day inspection window begins from the confirmed delivery date.
Transit Times by Region
Estimated time in transit
Transit estimates run from dispatch date and exclude customs clearance time, which varies by country and commodity.
| Region | Est. Transit | Notes |
|---|---|---|
| EU & UK | 7–14 days | Import duties and VAT assessed at customs — payable by buyer. REACH compliance documentation available on request. |
| GCC / Middle East | 5–10 days | Customs clearance handled by buyer or nominated freight agent. Certificate of Origin available on request. |
| ASEAN | 4–8 days | Country-specific import licences or permits may apply for certain actives. Buyer is responsible for pre-shipment compliance checks. |
| North America | 7–14 days | FDA Prior Notice may be required for cosmetic actives. Buyers are advised to confirm import classification before ordering. |
| Other Regions | 10–20 days | Contact us to confirm shipping availability and any documentation requirements specific to your country. |
All transit times are estimates only · Delays may occur due to customs inspection, public holidays, or carrier disruption
Freight & Documentation
Costs and paperwork
Freight is quoted individually based on weight, destination, and Incoterm. Full shipping documentation is prepared for every order.
Freight Policy
—Freight cost quoted at order confirmation
—Rates based on gross weight, destination, and selected Incoterm
—Express courier (DHL / FedEx / UPS) available on request
—Sea freight available for larger bulk orders
—Import duties and local taxes are the buyer's responsibility
Documents Included
✓Commercial Invoice
✓Packing List
✓Certificate of Analysis (batch-specific)
✓MSDS / Safety Data Sheet
✓Certificate of Origin — on request
Need a freight quote or shipping advice?
Email us with your destination, estimated order weight, and preferred Incoterm — we'll respond within 1 business day.
Global shipping
EU · GCC · ASEAN · Americas
Samples ≤7 working days
From order confirmation
Full documentation
COA · MSDS · Invoice · Packing list
Tamper-evident packing
UV-protected, sealed containers
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